Computational approach to neural plasticity of nervous system on system level

Abstract

Neuroplasticity (brain plasticity, cortical plasticity) is perceived an ability of nervous system to be changed (both in functional and structural areas) by processed signals (i. e. through activity, changes in environment, etc.). Better understanding of the mechanisms underlying neuroplasticity on the system level may benefit newest therapy strategies designed to more effectively promote recovery of function. It can help guide and focus research and clinical practice to greater efficacy and better functional outcomes in neurorehabilitation and increased patients quality of life. Computational models of processes associated with neuroplasticity on system level may be especially useful for deriving possible neuroplasticity mechanisms. This article aims at investigating the extent to which the available opportunities are being exploited, including own concepts, research and observations.